In Vivo Optical Imaging Publications
February 1, 2008
Noninvasive Real-time Imaging of Tumors and Metastases Using Tumor-targeting Light-emitting Escherichia coliMol Imaging Biol
Min, J. J.; Kim, H. J.; Park, J. H.; Moon, S.; Jeong, J. H.; Hong, Y. J.; Cho, K. O.; Nam, J. H.; Kim, N.; Park, Y. K.; Bom, H. S.; Rhee, J. H.; Choy, H. E.
January 26, 2008
In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancerClin Exp Metastasis
Jenkins, D. E.; Yu, S. F.; Hornig, Y. S.; Purchio, T.; Contag, P. R.
January 24, 2008
Nuclear Factor-{kappa}B Affects Tumor Progression in a Mouse Model of Malignant Pleural EffusionAm. J. Respir. Cell Mol. Biol.
Stathopoulos, Georgios T.; Zhu, Zhiwen; Everhart, M. Brett; Kalomenidis, Ioannis; Lawson, William E.; Bilaceroglu, Semra; Peterson, Todd E.; Mitchell, Daphne; Yull, Fiona E.; Light, Richard W.; Blackwell, Timothy S.
January 23, 2008
Bioluminescence Imaging of Systemic Tumor Targeting Using a Prostate-Specific Lentiviral VectorHuman Gene Therapy
Iyer, Meera; Salazar, Felix B.; Wu, Lily; Carey, Michael; Gambhir, Sanjiv S.
January 23, 2008
Development of bioluminescent Edwardsiella ictaluri for noninvasive disease monitoringKarsi, Attila; Menanteau-Ledouble, Simon; Lawrence, Mark L.
January 23, 2008
In vivo monitoring of DNA vaccine gene expression using firefly luciferase as a naked DNAVaccine
Jeon, Yong Hyun; Choi, Yun; Kang, Joo Hyun; Chung, June-Key; Lee, Yong Jin; Kim, Chul Woo; Jeong, Jae Min; Lee, Dong Soo; Lee, Myung Chul
January 23, 2008
NF-kappaB is essential for the progression of KSHV- and EBV-infected lymphomas in vivoBlood
Keller, S. A.; Hernandez-Hopkins, D.; Vider, J.; Ponomarev, V.; Hyjek, E.; Schattner, E. J.; Cesarman, E.
January 23, 2008
Second-generation triple reporter for bioluminescence, micro-positron emission tomography, and fluorescence imagingMol Imaging
Kesarwala, A. H.; Prior, J. L.; Sun, J.; Harpstrite, S. E.; Sharma, V.; Piwnica-Worms, D.
January 1, 2008
Molecular imaging of NF-kappaB in prostate tissue after systemic administration of IL-1betaProstate
Vykhovanets, E. V.; Shukla, S.; Maclennan, G. T.; Resnick, M. I.; Carlsen, H.; Blomhoff, R.; Gupta, S.
January 1, 2008
TLR3 Increases Disease Morbidity and Mortality from Vaccinia InfectionJ Immunol
Hutchens, M.; Luker, K. E.; Sottile, P.; Sonstein, J.; Lukacs, N. W.; Nunez, G.; Curtis, J. L.; Luker, G. D.
December 31, 2007
Bioluminescent imaging to monitor tumor progression and metastasis in live animalJ Soc Biol
Kauskot, A.; Manent, J.; Chareyre, F.; Cominetti, M.; Chopin, M.; Giovannini, M.; Legrand, C.; Bonnefoy, A.
December 31, 2007
Switching on the lights for gene therapyWinkeler, A.; Sena-Esteves, M.; Paulis, L. E.; Li, H.; Waerzeggers, Y.; Ruckriem, B.; Himmelreich, U.; Klein, M.; Monfared, P.; Rueger, M. A.; Heneka, M.; Vollmar, S.; Hoehn, M.; Fraefel, C.; Graf, R.; Wienhard, K.; Heiss, W. D.; Jacobs, A. H.
December 21, 2007
Genetic analysis of varicella-zoster virus ORF0 to ORF4 by use of a novel luciferase bacterial artificial chromosome systemJ Virol
Zhang, Z.; Rowe, J.; Wang, W.; Sommer, M.; Arvin, A.; Moffat, J.; Zhu, H.
December 21, 2007
The role of actively released fibrin-conjugated VEGF for VEGF receptor 2 gene activation and the enhancement of angiogenesisBiomaterials
Ehrbar, M.; Zeisberger, S. M.; Raeber, G. P.; Hubbell, J. A.; Schnell, C.; Zisch, A. H.
December 20, 2007
Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac functionCloning Stem Cells
: Xie, X.; Cao, F.; Sheikh, A. Y.; Li, Z.; Connolly, A. J.; Pei, X.; Li, R. K.; Robbins, R. C.; Wu, J. C.
December 19, 2007
Bone marrow-derived myofibroblasts contribute functionally to scar formation after myocardial infarctionvan Amerongen, M.; Bou-Gharios, G.; Popa, E.; van Ark, J.; Petersen, A.; van Dam, G.; van Luyn, M.; Harmsen, M.
December 19, 2007
In vivo imaging of gene transfer to the respiratory tractBiomaterials
Griesenbach, U.; Meng, C.; Farley, R.; Cheng, S. H.; Scheule, R. K.; Davies, M. H.; Wolstenholme-Hogg, P. C.; Ten Hove, W.; van der Hoeven, P.; Sinn, P. L.; McCray, P. B., Jr.; Inoue, M.; Geddes, D. M.; Hasegawa, M.; Frankel, G.; Wiles, S.; Alton, E. W.
December 18, 2007
Herpes Simplex Virus ThymidineUltrasound Med Biol
Aoi, A.; Watanabe, Y.; Mori, S.; Takahashi, M.; Vassaux, G.; Kodama, T.
December 15, 2007
Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivoStem Cells
Duan, Y.; Catana, A.; Meng, Y.; Yamamoto, N.; He, S.; Gupta, S.; Gambhir, S. S.; Zern, M. A.
December 15, 2007
Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironmentCancer research
Klopp, A. H.; Spaeth, E. L.; Dembinski, J. L.; Woodward, W. A.; Munshi, A.; Meyn, R. E.; Cox, J. D.; Andreeff, M.; Marini, F. C.
December 5, 2007
Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasisCanon, J. R.; Roudier, M.; Bryant, R.; Morony, S.; Stolina, M.; Kostenuik, P. J.; Dougall, W. C.
December 1, 2007
A universal technology for monitoring G-protein-coupled receptor activation in vitro and noninvasively in live animalsFaseb J
von Degenfeld, G.; Wehrman, T. S.; Hammer, M. M.; Blau, H. M.
December 1, 2007
A validated mouse model for orthotopic bladder cancer using transurethral tumour inoculation and bioluminescence imagingBJU Int
Hadaschik, B. A.; Black, P. C.; Sea, J. C.; Metwalli, A. R.; Fazli, L.; Dinney, C. P.; Gleave, M. E.; So, A. I.
December 1, 2007
Creation and Characterization of a Doxycycline-Inducible Mouse Model of Thyroid-Targeted RET/PTC1 Oncogene and Luciferase Reporter Gene CoexpressionThyroid
Knostman, K. A.; Venkateswaran, A.; Zimmerman, B.; Capen, C. C.; Jhiang, S. M.
December 1, 2007
Host-derived interleukin-18 differentially impacts regulatory and conventional T cell expansion during acute graft-versus-host diseaseBiol Blood Marrow Transplant
Zeiser, R.; Zambricki, E. A.; Leveson-Gower, D.; Kambham, N.; Beilhack, A.; Negrin, R. S.
December 1, 2007
Imaging of Mesenchymal Stem Cell Transplant by Bioluminescence and PETJ Nucl Med
Love, Z.; Wang, F.; Dennis, J.; Awadallah, A.; Salem, N.; Lin, Y.; Weisenberger, A.; Majewski, S.; Gerson, S.; Lee, Z.
December 1, 2007
Tracking the migration of dendritic cells by in vivo optical imagingNeoplasia
Pham, W.; Xie, J.; Gore, J. C.
November 28, 2007
Optimization of Topical Therapy for Leishmania major Localized Cutaneous Leishmaniasis Using a Reliable C57BL/6 ModelPLoS Negl Trop Dis
Lecoeur, H.; Buffet, P.; Morizot, G.; Goyard, S.; Guigon, G.; Milon, G.; Lang, T.
November 1, 2007
Chemotherapeutic agents up-regulate the cytomegalovirus promoter: implications for bioluminescence imaging of tumor response to therapyCancer Res
Svensson, R. U.; Barnes, J. M.; Rokhlin, O. W.; Cohen, M. B.; Henry, M. D.
November 1, 2007
CREB is a critical regulator of normal hematopoiesis and leukemogenesisBlood
Cheng, J. C.; Kinjo, K.; Judelson, D.; Chang, J.; Wu, W. S.; Schmid, I.; Shankar, D. B.; Kasahara, N.; Stripecke, R.; Bhatia, R.; Landaw, E. M.; Sakamoto, K. M.
November 1, 2007
Efficient and stable transgene expression in human embryonic stem cells using transposon-mediated gene transferStem Cells
Wilber, A.; Linehan, J. L.; Tian, X.; Woll, P. S.; Morris, J. K.; Belur, L. R.; McIvor, R. S.; Kaufman, D. S.
November 1, 2007
Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitisJ Clin Invest
Luo, J.; Ho, P. P.; Buckwalter, M. S.; Hsu, T.; Lee, L. Y.; Zhang, H.; Kim, D. K.; Kim, S. J.; Gambhir, S. S.; Steinman, L.; Wyss-Coray, T.
November 1, 2007
Imaging of hypoxia-driven gene expression in an orthotopic liver tumor modelMol Cancer Ther
Brader, P.; Riedl, C. C.; Woo, Y.; Ponomarev, V.; Zanzonico, P.; Wen, B.; Cai, S.; Hricak, H.; Fong, Y.; Blasberg, R.; Serganova, I.
November 1, 2007
In situ pulmonary localization of air pollution particle-induced oxidative stressRoberts, E. S.; Malstrom, S. E.; Dreher, K. L.
October 19, 2007
A novel alpha(v)beta (3)-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasisRamos, O. H.; Kauskot, A.; Cominetti, M. R.; Bechyne, I.; Salla Pontes, C. L.; Chareyre, F.; Manent, J.; Vassy, R.; Giovannini, M.; Legrand, C.; Selistre-de-Araujo, H. S.; Crepin, M.; Bonnefoy, A.
October 19, 2007
Multimodality imaging of vascular endothelial growth factor and vascular endothelial growth factor receptor expressionFront Biosci
Cai, W., Chen, X.
October 18, 2007
Inhibition of In Vivo Tumor Angiogenesis and Growth Via Systemic Delivery of an Angiopoietin 2-specific RNA AptamerJ Surg Res
Sarraf-Yazdi, S.; Mi, J.; Moeller, B. J.; Niu, X.; White, R. R.; Kontos, C. D.; Sullenger, B. A.; Dewhirst, M. W.; Clary, B. M.
October 14, 2007
Utility of TK/GCV in the context of highly effective oncolysis mediated by a serotype 3 receptor targeted oncolytic adenovirusGene Ther
Raki, M.; Hakkarainen, T.; Bauerschmitz, G. J.; Sarkioja, M.; Desmond, R. A.; Kanerva, A.; Hemminki, A.
October 9, 2007
Applications of bioluminescence imaging to the study of infectious diseasesCell Microbiol
Hutchens, M.; Luker, G. D.
October 3, 2007
Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assaysJ Am Chem Soc
Levi, J.; De, A.; Cheng, Z.; Gambhir, S. S.
October 1, 2007
ABCG2/BCRP Expression Modulates D-Luciferin Based Bioluminescence ImagingCancer Res
: Zhang, Y.; Bressler, J. P.; Neal, J.; Lal, B.; Bhang, H. E.; Laterra, J.; Pomper, M. G.
October 1, 2007
Bioluminescent mammalian cells grown in sponge matrices to monitor immune rejectionMol Imaging
Ojogho, O.; Li, A.; Zuppan, C. W.; Escher, A.
October 1, 2007
Cell Cycle Dependent and Schedule-Dependent Antitumor Effects of Sorafenib Combined with RadiationCancer Res
Plastaras, J. P.; Kim, S. H.; Liu, Y. Y.; Dicker, D. T.; Dorsey, J. F.; McDonough, J.; Cerniglia, G.; Rajendran, R. R.; Gupta, A.; Rustgi, A. K.; Diehl, J. A.; Smith, C. D.; Flaherty, K. T.; El-Deiry, W. S.
October 1, 2007
In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticlesNat Mater
Lee, D.; Khaja, S.; Velasquez-Castano, J. C.; Dasari, M.; Sun, C.; Petros, J.; Taylor, W. R.; Murthy, N.
October 1, 2007
Live imaging of Smad2/3 signaling in mouse skin wound healingWound Repair Regen
: Chong, A. K.; Satterwhite, T.; Pham, H. M.; Costa, M. A.; Luo, J.; Longaker, M. T.; Wyss-Coray, T.; Chang, J.
October 1, 2007
Noninvasive nuclear factor-kappaB bioluminescence imaging for the assessment of host-biomaterial interaction in transgenic miceBiomaterials
Ho, T. Y.; Chen, Y. S.; Hsiang, C. Y.
October 1, 2007
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probesNat Chem Biol
Blum, G.; von Degenfeld, G.; Merchant, M. J.; Blau, H. M.; Bogyo, M.
October 1, 2007
Targeted Proapoptotic Anticancer Drug Delivery SystemMol Pharm
: Chandna, P.; Saad, M.; Wang, Y.; Ber, E.; Khandare, J.; Vetcher, A. A.; Soldatenkov, V. A.; Minko, T.
October 1, 2007
Treatment of metastatic renal cancer with capsid-modified oncolytic adenovirusesMol Cancer Ther
Guse, K.; Ranki, T.; Ala-Opas, M.; Bono, P.; Sarkioja, M.; Rajecki, M.; Kanerva, A.; Hakkarainen, T.; Hemminki, A.
September 21, 2007
In vivo fluorescence imaging of the reticuloendothelial system using quantum dots in combination with bioluminescent tumour monitoringEur J Nucl Med Mol Imaging
Inoue, Y.; Izawa, K.; Yoshikawa, K.; Yamada, H.; Tojo, A.; Ohtomo, K.
September 20, 2007
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2Nature
Dentin, R.; Liu, Y.; Koo, S. H.; Hedrick, S.; Vargas, T.; Heredia, J.; Yates, J., 3rd; Montminy, M.
September 15, 2007
Localized recrudescence of Toxoplasma infections in the central nervous system of immunocompromised mice assessed by in vivo bioluminescence imagingMicrobes Infect
Dellacasa-Lindberg, I.; Hitziger, N.; Barragan, A.
September 13, 2007
MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessmentLeukemia
Stubbs, M. C.; Kim, Y. M.; Krivtsov, A. V.; Wright, R. D.; Feng, Z.; Agarwal, J.; Kung, A. L.; Armstrong, S. A.
September 12, 2007
Prolonged In Vivo Gene Silencing by Electroporation-Mediated Plasmid Delivery of Small Interfering RNAHum Gene Ther
Eefting, D.; Grimbergen, J. M.; De Vries, M. R.; Van Weel, V.; Kaijzel, E. L.; Que, I.; Moon, R. T.; Lowik, C. W.; Van Bockel, J. H.; Quax, P. H.
September 11, 2007
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart diseaseCirculation
Li, Z.; Wu, J. C.; Sheikh, A. Y.; Kraft, D.; Cao, F.; Xie, X.; Patel, M.; Gambhir, S. S.; Robbins, R. C.; Cooke, J. P.; Wu, J. C.
September 3, 2007
Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cellsOncogene
Wendt, M. K.; Cooper, A. N.; Dwinell, M. B.
September 1, 2007
CD101 Surface Expression Discriminates Potency Among Murine FoxP3+ Regulatory T CellsJ Immunol
Fernandez, I.; Zeiser, R.; Karsunky, H.; Kambham, N.; Beilhack, A.; Soderstrom, K.; Negrin, R. S.; Engleman, E.
September 1, 2007
Radiosensitization and modulation of p44/42 mitogen-activated protein kinase by 2-Methoxyestradiol in prostate cancer modelsCancer Res
Casarez, E. V.; Dunlap-Brown, M. E.; Conaway, M. R.; Amorino, G. P.
September 1, 2007
The PilA protein of non-typeable Haemophilus influenzae plays a role in biofilm formation, adherence to epithelial cells and colonization of the mammalian upper respiratory tractMol Microbiol
Jurcisek, J. A.; Bookwalter, J. E.; Baker, B. D.; Fernandez, S.; Novotny, L. A.; Munson, R. S., Jr.; Bakaletz, L. O.
September 1, 2007
Virus distribution of the attenuated MVA and NYVAC poxvirus strains in miceJ Gen Virol
Gomez, C. E.; Najera, J. L.; Domingo-Gil, E.; Ochoa-Callejero, L.; Gonzalez-Aseguinolaza, G.; Esteban, M.
August 29, 2007
Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2m(null) miceExp Hematol
Nervi, B.; Rettig, M. P.; Ritchey, J. K.; Wang, H. L.; Bauer, G.; Walker, J.; Bonyhadi, M. L.; Berenson, R. J.; Prior, J. L.; Piwnica-Worms, D.; Nolta, J. A.; Dipersio, J. F.
August 1, 2007
A new technique for physiodesis using photodynamic therapyClin Orthop Relat Res
Bisland, S. K.; Johnson, C.; Diab, M.; Wilson, B. C.; Burch, S.
August 1, 2007
Bortezomib inhibits angiogenesis and reduces tumor burden in a murine model of neuroblastomaSurgery
Hamner, J. B.; Dickson, P. V.; Sims, T. L.; Zhou, J.; Spence, Y.; Ng, C. Y.; Davidoff, A. M.
August 1, 2007
In vivo imaging in experimental preclinical tumor research--a reviewCytometry A
Wessels, J. T.; Busse, A. C.; Mahrt, J.; Dullin, C.; Grabbe, E.; Mueller, G. A.
August 1, 2007
Optical imaging of tumor cells in hollow fibers: evaluation of the antitumor activities of anticancer drugs and target validationNeoplasia
Zhang, G. J.; Chen, T. B.; Bednar, B.; Connolly, B. M.; Hargreaves, R.; Sur, C.; Williams, D. L.
August 1, 2007
Real-time imaging of astrocyte response to quantum dots: in vivo screening model system for biocompatibility of nanoparticlesNano Lett
Maysinger, D.; Behrendt, M.; Lalancette-Hebert, M.; Kriz, J.
August 1, 2007
Restricted tissue tropism and acquired resistance to Sindbis viral vector expression in the absence of innate and adaptive immunityGene Ther
Tseng, J. C.; Zheng, Y.; Yee, H.; Levy, D. E.; Meruelo, D.
August 1, 2007
Vav promoter-tTA conditional transgene expression system for hematopoietic cells drives high level expression in developing B and T cellsExp Hematol
Kim, W. I.; Wiesner, S. M.; Largaespada, D. A.
July 20, 2007
Potentiation of antileukemic therapies by Smac mimetic, LBW242: effects on mutant FLT3-expressing cellsMol Cancer Ther
Weisberg, E.; Kung, A. L.; Wright, R. D.; Moreno, D.; Catley, L.; Ray, A.; Zawel, L.; Tran, M.; Cools, J.; Gilliland, G.; Mitsiades, C.; McMillin, D. W.; Jiang, J.; Hall-Meyers, E.; Griffin, J. D.
July 16, 2007
Non-capsulated toxinogenic Bacillus anthracis present a specific growth and dissemination pattern in naive and PA-immune miceInfect Immun
Glomski, I. J., Corre, J. P., Mock, M., Goossens, P. L.
July 15, 2007
Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer fociCancer Res
Veiseh, M., Gabikian, P., Bahrami, S. B., Veiseh, O., Zhang, M., Hackman, R. C., Ravanpay, A. C., Stroud, M. R., Kusuma, Y., Hansen, S. J., Kwok, D., Munoz, N. M., Sze, R. W., Grady, W. M., Greenberg, N. M., Ellenbogen, R. G., Olson, J. M.
July 15, 2007
Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer modelClin Cancer Res
Verheul, H. M.; Hammers, H.; van Erp, K.; Wei, Y.; Sanni, T.; Salumbides, B.; Qian, D. Z.; Yancopoulos, G. D.; Pili, R.
July 12, 2007
Molecular Imaging of Bone Marrow Mononuclear Cell Homing and Engraftment in Ischemic MyocardiumSheikh, A. Y.; Lin, S. A.; Cao, F.; Cao, Y. A.; van der Bogt, K. E.; Chu, P.; Chang, C. P.; Contag, C. H.; Robbins, R. C.; Wu, J. C.
June 15, 2007
Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculatureMol Cancer Res
Dickson, P. V.; Hamner, J. B.; Streck, C. J.; Ng, C. Y.; McCarville, M. B.; Calabrese, C.; Gilbertson, R. J.; Stewart, C. F.; Wilson, C. M.; Gaber, M. W.; Pfeffer, L. M.; Skapek, S. X.; Nathwani, A. C.; Davidoff, A. M.
June 15, 2007
Multimodality imaging: novel pharmacological applications of reporter systemsQ J Nucl Med Mol Imaging
Stell, A.; Belcredito, S.; Ramachandran, B.; Biserni, A.; Rando, G.; Ciana, P.; Maggi, A.
June 14, 2007
Control of mesothelin-expressing ovarian cancer using adoptive transfer of mesothelin peptide-specific CD8(+) T cellsGene Ther
Hung, C. F.; Tsai, Y. C.; He, L.; Wu, T. C.
June 11, 2007
Significance of HIF-1-active cells in angiogenesis and radioresistanceOncogene
Harada, H.; Kizaka-Kondoh, S.; Li, G.; Itasaka, S.; Shibuya, K.; Inoue, M.; Hiraoka, M.
June 7, 2007
Optical bioluminescence imaging of human ES cell progeny in the rodent CNSJ Neurochem
Bradbury, M. S., Tomishima, M., Panagiotakos, G., Chan, B. K., Zanzonico, P., Vider, J., Ponomarev, V., Studer, L., Tabar, V.
June 1, 2007
A novel method for imaging in vivo degradation of poly(l-glutamic Acid), a biodegradable drug carrierPharm Res
Melancon, M. P.; Wang, W.; Wang, Y.; Shao, R.; Ji, X.; Gelovani, J. G.; Li, C.
June 1, 2007
Functional imaging of multidrug resistance in an orthotopic model of osteosarcoma using (99m)Tc-sestamibiEur J Nucl Med Mol Imaging
Gomes, C. M.; Welling, M.; Que, I.; Henriquez, N. V.; van der Pluijm, G.; Romeo, S.; Abrunhosa, A. J.; Botelho, M. F.; Hogendoorn, P. C.; Pauwels, E. K.; Cleton-Jansen, A. M.
June 1, 2007
In vivo bioluminescence tumor imaging of RGD peptide-modified adenoviral vector encoding firefly luciferase reporter geneMol Imaging Biol
Niu, G.; Xiong, Z.; Cheng, Z.; Cai, W.; Gambhir, S. S.; Xing, L.; Chen, X.
June 1, 2007
Primary Involvement of Pharynx and Peyer's Patch in Inhalational and Intestinal AnthraxPLoS Pathog
Glomski, I. J., Piris-Gimenez, A., Huerre, M., Mock, M., Goossens, P. L.
May 31, 2007
Breast cancer metastasis to bone: evaluation of bioluminescent imaging and microSPECT/CT for detecting bone metastasis in immunodeficient miceClin Exp Metastasis
Cowey, S., Szafran, A. A., Kappes, J., Zinn, K. R., Siegal, G. P., Desmond, R. A., Kim, H., Evans, L., Hardy, R. W.
May 24, 2007
Delivery and Inhibition of Reporter Genes by Small Interfering RNAs in a Mouse Skin ModelJ Invest Dermatol
Wang, Q.; Ilves, H.; Chu, P.; Contag, C. H.; Leake, D.; Johnston, B. H.; Kaspar, R. L.
May 22, 2007
Potency of siRNA versus shRNA mediated knockdown in vivoJ Pharm Sci
McAnuff, M. A.; Rettig, G. R.; Rice, K. G.
May 18, 2007
Derivation of engraftable skeletal myoblasts from human embryonic stem cellsT. Barberi, M. Bradbury, Z. Dincer, G. Panagiotakos, N.D. Socci, L. Studer
May 15, 2007
Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing hostBlood
Liu, C.; Yu, S.; Kappes, J.; Wang, J.; Grizzle, W. E.; Zinn, K. R.; Zhang, H. G.
May 15, 2007
Non-invasive fluorescent imaging of gliosis in transgenic mice for profiling developmental neurotoxicityToxicol Appl Pharmacol
Ho, G.; Zhang, C.; Zhuo, L.
May 13, 2007
Immune Response to Firefly Luciferase as a Naked DNACancer Biol Ther
Jeon, Y. H.; Choi, Y.; Kang, J. H.; Kim, C. W.; Jeong, J. M.; Lee, D. S.; Chung, J. K.
May 7, 2007
Bioluminescence imaging for assessment and normalization in transfected cell arraysBiotechnol Bioeng
Pannier, A. K.; Ariazi, E. A.; Bellis, A. D.; Bengali, Z.; Jordan, V. C.; Shea, L. D.
May 4, 2007
Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock NetworkCell
Liu, A. C.; Welsh, D. K.; Ko, C. H.; Tran, H. G.; Zhang, E. E.; Priest, A. A.; Buhr, E. D.; Singer, O.; Meeker, K.; Verma, I. M.; Doyle, F. J., 3rd; Takahashi, J. S.; Kay, S. A.
May 1, 2007
Lentiviral Vectors with CMV or MHCII Promoters Administered In Vivo: Immune Reactivity Versus Persistence of ExpressionMol Ther
Kimura, T.; Koya, R. C.; Anselmi, L.; Sternini, C.; Wang, H. J.; Comin-Anduix, B.; Prins, R. M.; Faure-Kumar, E.; Rozengurt, N.; Cui, Y.; Kasahara, N.; Stripecke, R.
April 26, 2007
Current State of Imaging Protein-Protein Interactions In Vivo With Genetically Encoded ReportersAnnu Rev Biomed Eng
Villalobos, V., Naik, S., Piwnica-Worms, D.
April 23, 2007
Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat modelAmerican journal of obstetrics and gynecology
Toelen, J., Deroose, C. M., Gijsbers, R., Reumers, V. , Sbragia, L. N., Vets, S., Chitneni, S. K., Bormans, G., Mortelmans, L., Deprest, J. A., Debyser, Z.
April 22, 2007
Continuous Delivery of D-Luciferin by Implanted Micro-osmotic Pumps Enables True Real-Time Bioluminescence Imaging of Luciferase Activity In VivoMol Imaging
Gross, S., Abraham, U., Prior, J. L., Herzog, E. D., Piwnica-Worms, D.
April 22, 2007
Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat modelAm J Obstet Gynecol
Toelen, J., Deroose, C. M., Gijsbers, R., Reumers, V., Sbragia, L. N., Vets, S., Chitneni, S. K., Bormans, G., Mortelmans, L., Deprest, J. A., Debyser, Z
April 22, 2007
The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemiaExp Hematol
Tolar, J., Wang, X., Braunlin, E., McElmurry, R. T., Nakamura, Y., Bell, S., Xia, L., Zhang, J., Hu, Q., Panoskaltsis-Mortari, A., Zhang, J., Blazar, B. R.
April 19, 2007
Molecular imaging of embryonic stem cell misbehavior and suicide gene ablationCloning Stem Cells
Cao, F., Drukker, M., Lin, S., Sheikh, A. Y., Xie, X., Li, Z., Connolly, A. J., Weissman, I. L., Wu, J. C.
April 19, 2007
Targeted imaging of colonic tumors in smad3-/- mice discriminates cancer and inflammationMol Cancer Res
Deane, N. G., Manning, H. C., Foutch, A. C., Washington, M. K., Aronow, B. J., Bornhop, D. J., Coffey, R. J.
April 17, 2007
Messenger RNA as a Source of Transposase for Sleeping Beauty Transposon-mediated Correction of Hereditary Tyrosinemia Type IMol Ther
Wilber, A., Wangensteen, K. J., Chen, Y., Zhuo, L., Frandsen, J. L., Bell, J. B., Chen, Z. J., Ekker, S. C., McIvor, R. S., Wang, X.
April 1, 2007
Bioluminescence: the potential of a non-invasive bio-optical imaging technique and improvement of animal researchTijdschr Diergeneeskd
Hesselink, J. W.; van Dam, G. M.
April 1, 2007
Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjectsCancer Res
Ray, P.; Tsien, R.; Gambhir, S. S.
April 1, 2007
Topoisomerase Inhibition Accelerates Gene Expression after Adeno-associated Virus-mediated Gene Transfer to the Mammalian HeartMol Ther
Prasad, K. M.; Xu, Y.; Yang, Z.; Toufektsian, M. C.; Berr, S. S.; French, B. A.
March 19, 2007
Synthetic PEGylated Glycoproteins and Their Utility in Gene DeliveryBioconjugate chemistry
Chen, C. P., Kim, J. S., Liu, D., Rettig, G. R., McAnuff, M. A., Martin, M. E., Rice, K. G.
March 15, 2007
Noninvasive molecular imaging sheds light on the synergy between 5-fluorouracil and TRAIL/Apo2L for cancer therapyClin Cancer Res
Lee, K. C.; Hamstra, D. A.; Bhojani, M. S.; Khan, A. P.; Ross, B. D.; Rehemtulla, A.
March 15, 2007
Three-dimensional reconstruction of in vivo bioluminescent sources based on multispectral imagingJ Biomed Opt
Kuo, C.; Coquoz, O.; Troy, T. L.; Xu, H.; Rice, B. W.
March 13, 2007
Imaging the Modulation of Adenoviral Kinetics and Biodistribution for Cancer Gene TherapyMol Ther
Mocanu, J.; Yip, K.; Alajez, N.; Shi, W.; Li, J. H.; Lunt, S.; Moriyama, E.; Wilson, B.; Milosevic, M.; Lo, K.; van Rooijen, N.; Busson, P.; Bastianutto, C.; Liu, F. F.
March 6, 2007
Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse modelProstate
Hsieh, C. L.; Xie, Z.; Yu, J.; Martin, W. D.; Datta, M. W.; Wu, G. J.; Chung, L. W.
March 1, 2007
Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host diseaseBlood
Zeiser, R., Nguyen, V. H., Hou, J. Z., Beilhack, A., Zambricki, E., Buess, M., Contag, C. H., Negrin, R. S.
March 1, 2007
Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancerCancer Res
Nathan, C. A.; Amirghahari, N.; Rong, X.; Giordano, T.; Sibley, D.; Nordberg, M.; Glass, J.; Agarwal, A.; Caldito, G.
March 1, 2007
Monitoring of disease progression by bioluminescence imaging and magnetic resonance imaging in an animal model of hematologic malignancyExp Hematol
Inoue, Y.; Izawa, K.; Tojo, A.; Nomura, Y.; Sekine, R.; Oyaizu, N.; Ohtomo, K.
March 1, 2007
Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGelHsu, A. R.; Cai, W.; Veeravagu, A.; Mohamedali, K. A.; Chen, K.; Kim, S.; Vogel, H.; Hou, L. C.; Tse, V.; Rosenblum, M. G.; Chen, X.
March 1, 2007
Stem cell transplantation: the lung barrierTransplant Proc
Schrepfer, S.; Deuse, T.; Reichenspurner, H.; Fischbein, M. P.; Robbins, R. C.; Pelletier, M. P.
February 27, 2007
In vivo imaging of hepcidin promoter stimulation by iron and inflammationBlood Cells Mol Dis
Flanagan, J. M., Truksa, J., Peng, H., Lee, P., Beutler, E.
February 26, 2007
Murine alveolar macrophages limit replication of vaccinia virusVirology
Rivera, R.; Hutchens, M.; Luker, K. E.; Sonstein, J.; Curtis, J. L.; Luker, G. D.
February 23, 2007
Liver transduction with a simian virus 40 vector encoding insulin-like growth factor I reduces hepatic damage and the development of liver cirrhosisGene Ther
Vera, M., Sobrevals, L., Zaratiegui, M., Martinez, L., Palencia, B., Rodriguez, C. M., Prieto, J., Fortes, P.
February 19, 2007
CD4+CD25+ regulatory T-cell-inactivation in combination with adenovirus vaccines enhances T-cell responses and protects mice from tumor challengeCancer Gene Ther
Elia, L., Aurisicchio, L., Facciabene, A., Giannetti, P., Ciliberto, G., La Monica, N., Palombo, F.
February 13, 2007
Combinatorial Library Screening for Developing an Improved Split-Firefly Luciferase Fragment-Assisted Complementation System for Studying Protein-Protein InteractionsAnalytical Chem
Paulmurugan, R.; Gambhir, S. S.
February 6, 2007
Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cellsProc Natl Acad Sci U S A
Nguyen Huu, S.; Oster, M.; Uzan, S.; Chareyre, F.; Aractingi, S.; Khosrotehrani, K.
February 1, 2007
Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory diseaseJ Gen Virol
Ryman, K. D.; Gardner, C. L.; Meier, K. C.; Biron, C. A.; Johnston, R. E.; Klimstra, W. B.
February 1, 2007
Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexiaOncogene
Wu, Y., McRoberts, K., Berr, S. S., Frierson, H. F., Jr., Conaway, M., Theodorescu, D.
February 1, 2007
The Lon protease of Pseudomonas aeruginosa is induced by aminoglycosides and is involved in biofilm formation and motilityMicrobiology
Marr, A. K.; Overhage, J.; Bains, M.; Hancock, R. E.
January 25, 2007
Toxoplasma gondii: Inconsistent dissemination patterns following oral infection in miceExp Parasitol
Boyle, J. P., Saeij, J. P., Boothroyd, J. C.,
January 24, 2007
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomasNature
Xue, W., Zender, L., Miething, C., Dickins, R. A., Hernando, E., Krizhanovsky, V., Cordon-Cardo, C., Lowe, S. W.
January 22, 2007
Monocytes give rise to mucosal, but not splenic, conventional dendritic cellsJ Exp Med
Varol, C., Landsman, L., Fogg, D. K., Greenshtein, L., Gildor, B., Margalit, R., Kalchenko, V., Geissmann, F., Jung, S.
January 21, 2007
Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental arthritisArthritis Res Ther
Gould, D.; Yousaf, N.; Fatah, R.; Subang, M. C.; Chernajovsky, Y.
January 18, 2007
Gene expression imaging by enzymatic catalysis of a fluorescent probe via membrane-anchored beta-glucuronidaseGene Ther
Su, Y. C.; Chuang, K. H.; Wang, Y. M.; Cheng, C. M.; Lin, S. R.; Wang, J. Y.; Hwang, J. J.; Chen, B. M.; Chen, K. C.; Roffler, S.; Cheng, T. L.
January 15, 2007
Carrier Cell-based Delivery of an Oncolytic Virus Circumvents Antiviral ImmunityMol Ther
Power, A. T.; Wang, J.; Falls, T. J.; Paterson, J. M.; Parato, K. A.; Lichty, B. D.; Stojdl, D. F.; Forsyth, P. A.; Atkins, H.; Bell, J. C.
January 15, 2007
Intravascular administration of tumor tropic neural progenitor cells permits targeted delivery of interferon-beta and restricts tumor growth in a murine model of disseminated neuroblastomaJ Pediatr Surg
Dickson, P. V.; Hamner, J. B.; Burger, R. A.; Garcia, E.; Ouma, A. A.; Kim, S. U.; Ng, C. Y.; Gray, J. T.; Aboody, K. S.; Danks, M. K.; Davidoff, A. M.
January 14, 2007
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expressionNature
Wan, Y. Y., Flavell, R. A.
January 14, 2007
Vaccinia virus preferentially infects and controls human and murine ovarian tumors in miceGene Ther
Hung, C. F.; Tsai, Y. C.; He, L.; Coukos, G.; Fodor, I.; Qin, L.; Levitsky, H.; Wu, T. C.
January 8, 2007
COX-2 involvement in breast cancer metastasis to boneOncogene
Singh, B.; Berry, J. A.; Shoher, A.; Ayers, G. D.; Wei, C.; Lucci, A.
January 2, 2007
Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritisArthritis Rheum
Izmailova, E. S.; Paz, N.; Alencar, H.; Chun, M.; Schopf, L.; Hepperle, M.; Lane, J. H.; Harriman, G.; Xu, Y.; Ocain, T.; Weissleder, R.; Mahmood, U.; Healy, A. M.; Jaffee, B.
January 1, 2007
A heparan sulfate-targeted conditionally replicative adenovirus, Ad5.pk7-Delta24, for the treatment of advanced breast cancerGene Ther
Ranki, T.; Kanerva, A.; Ristimaki, A.; Hakkarainen, T.; Sarkioja, M.; Kangasniemi, L.; Raki, M.; Laakkonen, P.; Goodison, S.; Hemminki, A.
December 15, 2006
Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor modelCancer research
Kang, S. H.; Cho, H. T.; Devi, S.; Zhang, Z.; Escuin, D.; Liang, Z.; Mao, H.; Brat, D. J.; Olson, J. J.; Simons, J. W.; Lavallee, T. M.; Giannakakou, P.; Van Meir, E. G.; Shim, H.
December 15, 2006
Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studiesEuropean Journal of Cancer
Kemper, E. M.; Leenders, W.; Kusters, B.; Lyons, S.; Buckle, T.; Heerschap, A.; Boogerd, W.; Beijnen, J. H.; van Tellingen, O.
December 8, 2006
Transgenic mouse for conditional, tissue-specific Cox-2 overexpressionGenesis
Kamei Ken-ichiro, Tomo-o Ishikawa, Harvey R. Herschman
December 1, 2006
Genetically encoded optical probe for detecting release of proteins from mitochondria toward cytosol in living cells and mammalsAnal Chem
Kanno, A.; Ozawa, T.; Umezawa, Y.
December 1, 2006
T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cellsBlood
Vera, J.; Savoldo, B.; Vigouroux, S.; Biagi, E.; Pule, M.; Rossig, C.; Wu, J.; Heslop, H. E.; Rooney, C. M.; Brenner, M. K.; Dotti, G.
December 1, 2006
Visualization of antigen-specific T cell in living arthritic miceJ Nippon Med Sch
Nakajima, A.; Kamijo, S.; Yoshioka, T.
November 30, 2006
Fetal Gene Transfer Using Lentiviral Vectors: In Vivo Detection of Gene Expression by microPET and Optical Imaging in Fetal and Infant MonkeysHum Gene Ther
Tarantal, A. F., Lee, C. C., Jimenez, D. F., Cherry, S. R.
November 30, 2006
Fetal Gene Transfer Using Lentiviral Vectors: In Vivo Detection of Gene Expression by microPET and Optical Imaging in Fetal and Infant MonkeysHum Gene Ther
Tarantal, A. F., Lee, C. C., Jimenez, D. F., Cherry, S. R.
November 15, 2006
Differential Biodistribution of Adenoviral Vector In Vivo as Monitored by Bioluminescence Imaging and Quantitative Polymerase Chain ReactionHum Gene Ther
Johnson, M.; Huyn, S.; Burton, J.; Sato, M.; Wu, L.
November 15, 2006
Imaging mitogen-activated protein kinase function in xenograft models of prostate cancerCancer Res
Ilagan, R.; Pottratz, J.; Le, K.; Zhang, L.; Wong, S. G.; Ayala, R.; Iyer, M.; Wu, L.; Gambhir, S. S.; Carey, M.
November 13, 2006
Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapyOncogene
Yuan, L., Siegel, M., Choi, K., Khosla, C., Miller, C. R., Jackson, E. N., Piwnica-Worms, D., Rich, K. M.
November 1, 2006
In Vivo Imaging of Hepatic Growth Hormone SignalingMol Endocrinol
Frank, Stuart J., Wang, Xiangdong, He, Kai, Yang, Ning, Fang, Peng, Rosenfeld, Ron G., Hwa, Vivian, Chaudhuri, Tandra R., Deng, Luqin, Zinn, Kurt R.
November 1, 2006
Transgenic Mouse Model for Rapid Pharmacodynamic Evaluation of AntiandrogensEllwood-Yen, Katharine, Wongvipat, John, Sawyers, Charles
October 24, 2006
An intramolecular folding sensor for imaging estrogen receptor-ligand interactionsPNAS
Paulmurugan, Ramasamy; Gambhir, Sanjiv S.
October 24, 2006
PGC-1alpha controls hepatitis B virus through nutritional signalsShlomai, A.; Paran, N.; Shaul, Y.
October 23, 2006
Labeling of human adipose-derived stem cells for non-invasive in vivo cell trackingCell and Tissue Banking
Wolbank S, Peterbauer A, Wassermann E, Hennerbichler S, van Griensven M, Duba H, Gabriel C, Redl H
October 23, 2006
In vitro validation of bioluminescent monitoring of disease progression and therapeutic response in leukaemia model animalsEuropean Journal of Nuclear Medicine and Molecular Imaging
Yusuke, Inoue, Arinobu, Tojo, Rieko, Sekine, Yasushi, Soda, Seiichiro, Kobayashi, Akiko, Nomura, Kiyoko, Izawa, Toshio, Kitamura, Toshiyuki, Okubo, Kuni, Ohtomo
October 23, 2006
Labelling of human adipose-derived stem cells for non-invasive in vivo cell trackingCell and Tissue Banking
Wolbank, Susanne, Anja, Peterbauer, Esther, Wassermann, Simone, Hennerbichler, Regina, Voglauer, Martijn van, Griensven, Hans-Christoph, Duba, Christian, Gabriel, Heinz, Redl
October 23, 2006
Luminescent imaging of [beta]-galactosidase activity in living subjects using sequential reporter-enzyme luminescenceNat Meth
Wehrman, Thomas S., von Degenfeld, Georges, Krutzik, Peter O., Nolan, Garry P., Blau, Helen M.
October 23, 2006
Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effectNeurosurgery
Szentirmai O., Baker C.H.,, Lin N., Szucs S., Takahashi M., Kiryu S., Kung A.L., Mulligan R.C., Carter B.S.
October 23, 2006
Noninvasive Optical Tracking of Red Fluorescent ProteinExpressing Cancer Cells in a Model of Metastatic Breast CancerNeoplasia
Winnard, Paul T., Kluth, Jessica B., Raman, Venu
October 23, 2006
Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cellsWu JC, Feng Cao Sucharita Dutta Xiaoyan Xie Elmer Kim Neil Chungfat Sanjiv Gambhir Sean Mathewson Andrew J. Connolly Matthew Brown Evelyn W. Wang
October 23, 2006
RNA as a Source of Transposase for Sleeping Beauty-Mediated Gene Insertion and Expression in Somatic Cells and TissuesMolecular Therapy
Wilber, Andrew, Frandsen, Joel L., Geurts, Jennifer L., Largaespada, David A., Hackett, Perry B., McIvor, R. Scott
October 23, 2006
The effect of zoledronic acid and osteoprotegerin on growth of human lung cancer in the tibias of nude miceClinical and Experimental Metastasis
S. H. Tannehill-Gregg, A. L. Levine, M. V. P. Nadella, H. Iguchi, T. J. Rosol
October 22, 2006
"Firefly Rats" as an Organ/Cellular Source for Long-Term In Vivo Bioluminescent Imaging. [Article]Transplantation
Hakamata, Yoji, Murakami, Takashi, Kobayashi, Eiji
October 22, 2006
Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposonBMC Biotechnology
Geurts, Aron, Wilber, Andrew, Carlson, Corey, Lobitz, Paul, Clark, Karl, Hackett, Perry, McIvor, R. Scott, Largaespada, David
October 22, 2006
In vivo electroporation and ubiquitin promoter - a protocol for sustained gene expression in the lungThe Journal of Gene Medicine
Gazdhar Amiq, Murat Bilici, Jaroslaw Pierog, Erick L. Ayuni, Mathias Gugger, Antoinette Wetterwald, Marco Cecchini, Ralph Alexander Schmid
October 22, 2006
Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effectNeurosurgery
Szentirmai O, Baker CH, Lin N, Szucs S, Takahashi M, Kiryu S, Kung AL, Mulligan RC, Carter BS
October 22, 2006
Noninvasive Evaluation of Immunosuppressive Drug Efficacy on Acute Donor Cell SurvivalMolecular Imaging and BIology
Gheysens,Olivier, Shuan, Lin, Feng, Cao, Dongxu, Wang, Ian, Y. Chen
October 22, 2006
Regulation of the Atm promoter in vivoGenes, Chromosomes and Cancer
Gueven, N., Fukao, T., Luff, J., Paterson, C., Kay, G., Kondo, N., Lavin, M. F.
October 22, 2006
The effect of zoledronic acid and osteoprotegerin on growth of human lung cancer in the tibias of nude miceClinical and Experimental Metastasis
S. H. Tannehill-Gregg, A. L. Levine, M. V. P. Nadella, H. Iguchi, T. J. Rosol
October 19, 2006
Bioluminescent quantum dotsNat Meth
Evanko, Daniel
October 19, 2006
In Vivo Bioluminescence Imaging of Transplanted Islets and Early Detection of Graft Rejection. [Article]Chen, Xiaojuan, Zhang, Xiaomin, Larson, Courtney S., Baker, Marshall S., Kaufman, Dixon B.
October 19, 2006
In vivo molecular imaging of adenoviral versus lentiviral gene therapy in two bone formation modelsJournal of Orthopaedic Research
Brian T. Feeley, Augustine H. Conduah Osamu Sugiyama Lucie Krenek Irvin S. Y. Chen Jay R. Lieberman
October 19, 2006
Non-invasive bioluminescence imaging for monitoring herpes simplex virus type 1 hematogenous infectionMicrobes and Infection
Burgos, Javier S., Guzman-Sanchez, Fernando, Sastre, Isabel, Fillat, Cristina, Valdivieso, Fernando
October 19, 2006
Noninvasive Monitoring of Long-Term Lentiviral Vector-Mediated Gene Expression in Rodent Brain with Bioluminescence ImagingMolecular Therapy
Bormans, Guy, Debyser, Zeger, Mortelmans, Luc, Baekelandt, Veerle
October 19, 2006
Visualizing fungal infections in living mice using bioluminescent pathogenic Candida albicans strains transformed with the firefly luciferase geneMicrobial Pathogenesis
Doyle, Timothy C., Nawotka, Kevin A., Kawahara, Carole Bellinger, Francis, Kevin P., Contag, Pamela R.
October 17, 2006
A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivoBritish Journal of Cancer
Sato K, Yuasa T, Nogawa M, Kimura S, Segawa H, Yokota A, Maekawa T
October 16, 2006
Monitoring of bactericidal action of laser by in vivo imaging of bioluminescent E. coli in a cutaneous wound infectionLasers in Medical Science
Samir Jawhara and Serge Mordon
October 15, 2006
Evaluation of DNA vaccination with recombinant adenoviruses using bioluminescence imaging of antigen expression: impact of application routes and delivery with dendritic cellsJ Gene Med
Schweichel, D.; Steitz, J.; Tormo, D.; Gaffal, E.; Ferrer, A.; Buchs, S.; Speuser, P.; Limmer, A.; Tuting, T.
October 15, 2006
Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virionMol Imaging
Matthews, Q. L.; Sibley, D. A.; Wu, H.; Li, J.; Stoff-Khalili, M. A.; Waehler, R.; Mathis, J. M.; Curiel, D. T.
October 12, 2006
In Vivo Near-Infrared Fluorescence Imaging of Integrin alpha V beta 3 in an Orthotopic Glioblastoma ModelMolecular Imaging and BIology
Hsu AR; Hou, LC; A, Veeravagu; Greve, JM; V, Hannes; V, Tse; X, Chen
October 12, 2006
Sarcoma derived from cultured mesenchymal stem cellsStem Cells
Tolar, J., Nauta, A. J., Osborn, M. J., Panoskaltsis Mortari, A., McElmurry, R. T., Bell, S., Xia, L., Zhou, N., Riddle, M., Schroeder, T. M.
October 12, 2006
Sarcoma derived from cultured mesenchymal stem cellsStem Cells
Tolar, J., Nauta, A. J., Osborn, M. J., Panoskaltsis Mortari, A., McElmurry, R. T., Bell, S., Xia, L., Zhou, N., Riddle, M., Schroeder, T. M., Westendorf, J. J., McIvor, R. S., Hogendoorn, P. C., Szuhai, K., Oseth, L., Hirsch, B., Yant, S. R.,
October 1, 2006
Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumorsProtein Engineering, Design and Selection
Venisnik, Katy M., Olafsen, Tove, Loening, Andreas M., Iyer, Meera, Gambhir, Sanjiv S., Wu, Anna M.
October 1, 2006
Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancerCancer
Sarkioja, M.; Kanerva, A.; Salo, J.; Kangasniemi, L.; Eriksson, M.; Raki, M.; Ranki, T.; Hakkarainen, T.; Hemminki, A.
October 1, 2006
Novel Robust Hepatitis C Virus Mouse Efficacy ModelAntimicrob. Agents Chemother.
Zhu, Qing, Oei, Yoko, Mendel, Dirk B., Garrett, Evelyn N., Patawaran, Montesa B., Hollenbach, Paul W., Aukerman, Sharon L., Weiner, Amy J.
September 15, 2006
Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cellsMol Cancer Ther
Khanbolooki, S.; Nawrocki, S. T.; Arumugam, T.; Andtbacka, R.; Pino, M. S.; Kurzrock, R.; Logsdon, C. D.; Abbruzzese, J. L.; McConkey, D. J.
September 15, 2006
Quantifying the Activity of Adenoviral E1A CR2 Deletion Mutants Using Renilla Luciferase Bioluminescence and 3'-Deoxy-3'-[18F]Fluorothymidine Positron Emission Tomography ImagingCancer Res
Leyton, Julius; Lockley, Michelle; Aerts, Joeri L.; Baird, Sarah K.; Aboagye, Eric O.; Lemoine, Nicholas R.; McNeish, Iain A.
September 15, 2006
Use of lipophilic near-infrared dye in whole-body optical imaging of hematopoietic cell homingJ Biomed Opt
Kalchenko, V.; Shivtiel, S.; Malina, V.; Lapid, K.; Haramati, S.; Lapidot, T.; Brill, A.; Harmelin, A.
September 1, 2006
Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantationNat Med
Zakrzewski, J. L.; Kochman, A. A.; Lu, S. X.; Terwey, T. H.; Kim, T. D.; Hubbard, V. M.; Muriglan, S. J.; Suh, D.; Smith, O. M.; Grubin, J.; Patel, N.; Chow, A.; Cabrera-Perez, J.; Radhakrishnan, R.; Diab, A.; Perales, M. A.; Rizzuto, G.; Menet, E.; Pamer
September 1, 2006
In Vivo Bioluminescence Imaging of the Murine Pathogen Citrobacter rodentiumInfection and Immunity
Siouxsie Wiles, Karen M. Pickard, Katian Peng, Thomas T. MacDonald, and Gad Frankel
September 1, 2006
In Vivo Bioluminescence Imaging of the Murine Pathogen Citrobacter rodentiumInfect. Immun.
Wiles, Siouxsie, Pickard, Karen M., Peng, Katian, MacDonald, Thomas T., Frankel, Gad
August 28, 2006
Evaluation of T cells as carriers for systemic measles virotherapy in the presence of antiviral antibodiesGene Ther
Ong, H. T.; Hasegawa, K.; Dietz, A. B.; Russell, S. J.; Peng, K. W.
August 25, 2006
Luciferin Derivatives for Enhanced in Vitro and in Vivo Bioluminescence AssaysBiochemistry
Shinde, R.; Perkins, J.; Contag, C. H.
August 19, 2006
Efficacy of zoledronate against neuroblastomaSurgery
Dickson, P. V., Hamner, J. B., Cauthen, L. A., Ng, C. Y., McCarville, M. B., Davidoff, A. M.
August 15, 2006
CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3-Expressing Orthotopic Multiple Myeloma Model in MiceClin Cancer Res
Xin, Xiaohua, Abrams, Tinya J., Hollenbach, Paul W., Rendahl, Katherine G., Tang, Yan, Oei, Yoko A., Embry, Millicent G., Swinarski, Debbie E., Garrett, Evelyn N., Pryer, Nancy K., Trudel, Suzanne, Jallal, Bahija, Mendel, Dirk B., Heise, Carla C.
August 1, 2006
A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6Cancer Res
Baughn, L. B.; Di Liberto, M.; Wu, K.; Toogood, P. L.; Louie, T.; Gottschalk, R.; Niesvizky, R.; Cho, H.; Ely, S.; Moore, M. A.; Chen-Kiang, S.
August 1, 2006
Real-time Evaluation of p53 Oscillatory Behavior In vivo Using Bioluminescent ImagingCancer Res
Hamstra, Daniel A., Griffin, Laura B., Laxman, Bharathi, Ross, Brian D., Rehemtulla, Alnawaz
July 18, 2006
Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenograftsPNAS
Wang, Wenge, Kim, Seok-Hyun, El-Deiry, Wafik S.
July 16, 2006
Real-time monitoring of stress erythropoiesis in vivo using Gata1 and beta-globin LCR luciferase transgenic miceBlood
Suzuki, M.; Ohneda, K.; Hosoya-Ohmura, S.; Tsukamoto, S.; Ohneda, O.; Philipsen, S.; Yamamoto, M.
July 15, 2006
High intensity focused ultrasound-induced gene activation in solid tumorsJ Acoust Soc Am
Liu, Y.; Kon, T.; Li, C.; Zhong, P.
July 15, 2006
p73 or p53 Directly Regulates Human p53 Transcription to Maintain Cell Cycle CheckpointsCancer Res
Wang, Shulin, El-Deiry, Wafik S.
July 8, 2006
Functions of CXCL12 and CXCR4 in breast cancerCancer Lett
Luker, K. E.; Luker, G. D.
July 4, 2006
Adenoviral Human BCL-2 Transgene Expression Attenuates Early Donor Cell Death After Cardiomyoblast Transplantation Into Ischemic Rat HeartsCirculation
Kutschka, Ingo; Kofidis, Theo; Chen, Ian Y.; von Degenfeld, Georges; Zwierzchoniewska, Monika; Hoyt, Grant; Arai, Takayasu; Lebl, Darren R.; Hendry, Stephen L.; Sheikh, Ahmad Y.; Cooke, David T.; Connolly, Andrew; Blau, Helen M.; Gambhir, Sanjiv S.; Robbi
July 4, 2006
Collagen Matrices Enhance Survival of Transplanted Cardiomyoblasts and Contribute to Functional Improvement of Ischemic Rat HeartsCirculation
Kutschka, Ingo; Chen, Ian Y.; Kofidis, Theo; Arai, Takayasu; von Degenfeld, Georges; Sheikh, Ahmad Y.; Hendry, Stephen L.; Pearl, Jeremy; Hoyt, Grant; Sista, Ramachadra; Yang, Phillip C.; Blau, Helen M.; Gambhir, Sanjiv S.; Robbins, Robert C.
July 1, 2006
Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencingBiotechnol Bioeng
Bartlett, D. W.; Davis, M. E.
July 1, 2006
Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 productionBlood
Zeiser, Robert, Nguyen, Vu H., Beilhack, Andreas, Buess, Martin, Schulz, Stephan, Baker, Jeanette, Contag, Christopher H., Negrin, Robert S.
June 15, 2006
EZC-Prostate Models Offer High Sensitivity and Specificity for Noninvasive Imaging of Prostate Cancer Progression and Androgen Receptor ActionCancer Res
Seethammagari, Mamatha R.; Xie, Xiaoming; Greenberg, Norman M.; Spencer, David M.
June 1, 2006
A Novel Noninvasive Model of Endometriosis for Monitoring the Efficacy of Antiangiogenic TherapyChristian M. Becker, Renee D. Wright, Ronit, Satchi-Fainaro, Tae Funakoshi, Judah Folkman, Andrew L. Kung, Robert J. D'Amato
June 1, 2006
In vivo imaging using bioluminescence: a tool for probing graft-versus-host diseaseNat Rev Immunol
Negrin, Robert S.; Contag, Christopher H.
May 22, 2006
Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activationBioconjugate chemistry
Goun, E. A., Shinde, R., Dehnert, K. W., Adams-Bond, A., Wender, P. A., Contag, C. H., Franc, B. L.
May 18, 2006
Near-Infrared Fluorescence Imaging of Tumor Integrin alpha(v)beta (3) Expression with Cy7-Labeled RGD MultimersMol Imaging Biol
Wu, Y., Cai, W., Chen, X.
May 17, 2006
Near-Infrared Fluorescent Deoxyglucose Analogue for Tumor Optical Imaging in Cell Culture and Living MiceBioconjugate Chem.
Cheng, Z., Levi, J., Xiong, Z., Gheysens, O., Keren, S., Chen, X., Gambhir, S. S.
May 15, 2006
In vitro validation of bioluminescent monitoring of disease progression and therapeutic response in leukaemia model animalsEuropean Journal of Nuclear Medicine and Molecular Imaging
Yusuke, Inoue; Arinobu, Tojo; Rieko, Sekine; Yasushi, Soda; Seiichiro, Kobayashi; Akiko, Nomura; Kiyoko, Izawa; Toshio, Kitamura; Toshiyuki, Okubo; Kuni, Ohtomo
May 15, 2006
Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptideCancer Res
Papo, N.; Seger, D.; Makovitzki, A.; Kalchenko, V.; Eshhar, Z.; Degani, H.; Shai, Y.
May 9, 2006
New bone formation and osteolysis by a metastatic, highly invasive canine prostate carcinoma xenograftThe Prostate
LeRoy B, Nanda K. Thudi Murali V. P. Nadella Ramiro E. Toribio Sarah H. Tannehill-Gregg Adrie van Bokhoven Deborah Davis Stephanie Corn Thomas J. Rosol
May 1, 2006
Noninvasive Bioluminescence Imaging of Normal and Spontaneously Transformed Prostate Tissue in MiceCancer Res
Lyons, Scott K.; Lim, Ed; Clermont, Anne O.; Dusich, Joan; Zhu, Lingyun; Campbell, Kenneth D.; Coffee, Richard J.; Grass, David S.; Hunter, John; Purchio, Tony; Jenkins, Darlene
May 1, 2006
Systemic effects of orally-administered zinc and tin (IV) metalloporphyrins on heme oxygenase expression in micePediatr Res
Morioka, I.; Wong, R. J.; Abate, A.; Vreman, H. J.; Contag, C. H.; Stevenson, D. K.
April 10, 2006
Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living miceVirology
Luker, Kathryn E.; Schultz, Tracey; Romine, Joseph; Leib, David A.; Luker, Gary D.
April 1, 2006
Bioluminescence Imaging of Live Infected Salmonids Reveals that the Fin Bases Are the Major Portal of Entry for NovirhabdovirusJ. Virol.
Harmache, Abdallah, LeBerre, Monique, Droineau, Stephanie, Giovannini, Marco, Bremont, Michel
March 24, 2006
Imaging Cyclooxygenase-2 (Cox-2) Gene Expression in Living Animals with a Luciferase Knock-in Reporter GeneMolecular Imaging and Biology
Ishikawa, Tomo O.; Naveen, K. Jain; Makoto, M. Taketo; Harvey, R. Herschman
March 24, 2006
Imaging Cyclooxygenase-2 (Cox-2) Gene Expression in Living Animals with a Luciferase Knock-in Reporter GeneMolecular Imaging and Biology
Ishikawa, Tomo O.; Naveen, K. Jain; Makoto, M. Taketo; Harvey, R. Herschman
March 24, 2006
Synergistic Antitumor Effects of Immune Cell-Viral BiotherapyScience
Thorne, Steve H., Negrin, Robert S., Contag, Christopher H.
March 24, 2006
Synergistic Antitumor Effects of Immune Cell-Viral BiotherapyScience
Thorne, Steve H., Negrin, Robert S., Contag, Christopher H.
March 15, 2006
Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical studyClin Cancer Res
Chan, J. K., Hamilton, C. A., Cheung, M. K., Karimi, M., Baker, J., Gall, J. M., Schulz, S., Thorne, S. H., Teng, N. N., Contag, C. H., Lum, L. G., Negrin, R. S.
March 15, 2006
Induced biliary excretion of Listeria monocytogenesInfect Immun
Hardy, J.; Margolis, J. J.; Contag, C. H.
March 1, 2006
A Comparison of Antiangiogenic Therapies for the Prevention of Liver MetastasesJournal of Surgical Research
Mi, Jing; Sarraf-Yazdi, Shiva; Zhang, Xiuwu; Cao, Yiting; Dewhirst, Mark W.; Kontos, Christopher D.; Li, Chuan-Yuan; Clary, Bryan M.
March 1, 2006
Spectral Unmixing of Multicolored Bioluminescence Emitted from Heterogeneous Biological SourcesAnal. Chem.
Gammon, S. T., Leevy, W. M., Gross, S., Gokel, G. W., Piwnica-Worms, D.
February 26, 2006
Self-illuminating quantum dot conjugates for in vivo imagingNat Biotech
So, Min-Kyung; Xu, Chenjie; Loening, Andreas M.; Gambhir, Sanjiv S.; Rao, Jianghong
February 26, 2006
Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transferThe Journal of Gene Medicine
Ogura Tsuyoshi, Hiroaki Mizukami Jun Mimuro Seiji Madoiwa Takashi Okada Takashi Matsushita Masashi Urabe Akihiro Kume Hiromi Hamada Hiroyuki Yoshikawa Yoichi Sakata Keiya Ozawa
February 21, 2006
In Vivo Visualization of Embryonic Stem Cell Survival, Proliferation, and Migration After Cardiac DeliveryCirculation
Cao, Feng, Lin, Shuan, Xie, Xiaoyan, Ray, Pritha, Patel, Manishkumar, Zhang, Xianzhong, Drukker, Micha, Dylla, Scott J., Connolly, Andrew J., Chen, Xiaoyuan, Weissman, Irving L., Gambhir, Sanjiv S., Wu, Joseph C.
February 15, 2006
Expression of firefly luciferase in Candida albicans and its use in the selection of stable transformantsMicrob Pathog
Doyle, T. C.; Nawotka, K. A.; Purchio, A. F.; Akin, A. R.; Francis, K. P.; Contag, P. R.
February 15, 2006
The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor {beta}-Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer CellsCancer Res
Deckers, Martine, van Dinther, Maarten, Buijs, Jeroen, Que, Ivo, Lowik, Clemens, van der Pluijm, Gabri
February 13, 2006
Quantitative bioluminescence imaging of transgene expression in vivoAnalytical Biochemistry
Rettig, Garrett R.; McAnuff, Marie; Liu, Dijie; Kim, Ji-Seon; Rice, Kevin G.
February 2, 2006
Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunityStem Cells
Tian, Xinghui, Woll, Petter S., Morris, Julie K., Linehan, Jonathan L., Kaufman, Dan S.
February 2, 2006
Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunityStem Cells
Tian, Xinghui, Woll, Petter S., Morris, Julie K., Linehan, Jonathan L., Kaufman, Dan S.
February 1, 2006
Visualization of Telomerase Reverse Transcriptase (hTERT) Promoter Activity Using a Trimodality Fusion Reporter ConstructJ Nucl Med
Padmanabhan, Parasuraman; Otero, Jesse; Ray, Pritha; Paulmurugan, Ramasamy; Hoffman, Andrew R.; Gambhir, Sanjiv S.; Biswal, Sandip; Ulaner, Gary A.
January 24, 2006
Spatiotemporal expression of heme oxygenase-1 detected by in vivo bioluminescence after hepatic ischemia in HO-1/luc miceLiver Transplantation
Huawei Su, Gooitzen M. van Dam Carlijn I. Buis Dorien S. Visser Jan Willem Hesselink Theo A. Schuurs Henri G. D. Leuvenink Christopher H. Contag Robert J.
January 23, 2006
A Novel Method of Monitoring Response to Islet Transplantation: Bioluminescent Imaging of an NF-kB Transgenic Mouse Model.Transplantation
Roth, David J.; Jansen, E. Duco; Powers, Alvin C.; Wang, Taylor G.
January 23, 2006
Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden.Neurosurgery
Prins, RM, Bruhn KW, Craft N, Lin JW, Kim CH, Odesa SK, Miller JF, Liau LM.
January 23, 2006
Efficient in vivo knock-down of estrogen receptor alpha: application of recombinant adenovirus vectors for delivery of short hairpin RNA.BMC Biotechnology
Krom, YD ; Fallaux, FJ ; Que, I; Lowik, C; van Dijk, KW
January 23, 2006
In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardiumAnnals of Nuclear Medicine
Min JJ, Ahn Y, Moon S, Kim YS, Park JE, Kim SM, Le UN, Wu JC, Joo SY, Hong MH, Yang DH, Jeong MH, Song CH, Jeong YH, Yoo KY, Kang KS, Bom HS
January 23, 2006
In vivo luminescent imaging of cyclosporin A-mediated cancer progression in ratsTransplantation
Ohsawa I, Murakami T, Uemoto S, Kobayashi E.
January 15, 2006
Activity of the Adenoviral E1A Deletion Mutant dl922-947 in Ovarian Cancer: Comparison with E1A Wild-type Viruses, Bioluminescence Monitoring, and Intraperitoneal Delivery in IcodextrinCancer Res
Lockley, Michelle; Fernandez, Mario; Wang, Yaohe; Li, N. Fiona; Conroy, Susan; Lemoine, Nicholas; McNeish, Iain
January 12, 2006
Host factors that impact the biodistribution and persistence of multipotent adult progenitor cellsBlood
Tolar, Jakub, O'Shaughnessy, Matthew J., Panoskaltsis-Mortari, Angela, McElmurry, Ron T., Bell, Scott, Riddle, Megan, McIvor, R. S., Yant, Stephen R., Kay, Mark A., Krause, Diane, Verfaillie, Catherine M., Blazar, Bruce R.
January 12, 2006
Host factors that impact the biodistribution and persistence of multipotent adult progenitor cellsBlood
Tolar, Jakub, O'Shaughnessy, Matthew J., Panoskaltsis-Mortari, Angela, McElmurry, Ron T., Bell, Scott, Riddle, Megan, McIvor, R. S., Yant, Stephen R., Kay, Mark A., Krause, Diane, Verfaillie, Catherine M., Blazar, Bruce R.
January 12, 2006
Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imagingDerek W. Bartlett, Mark E. Davis
January 12, 2006
Noninvasive indirect imaging of vascular endothelial growth factor gene expression using bioluminescence imaging in living transgenic micePhysiol. Genomics
Wang, Yanling, Iyer, Meera, Annala, Alexander, Wu, Lily, Carey, Michael, Gambhir, Sanjiv S.
January 10, 2006
Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integrationCarmen Bertoni, Sohail J