Caliper Owners Group (COG)

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COG is more than a collection of individuals using technologies from Caliper

It is an organization of innovative scientists deploying leading edge technologies to advance research and improve the human condition. COG provides a forum to network with colleagues, share best practices and participate in thought-leadership discussions.

The goals of COG and the annual meeting are to enable users to share best practices for instrument use and technology adoption; share feedback on future directions and key improvements requested; provide early access to new releases from Caliper; and create a networking event for users.

COG 2010 Presentations

Keynote Presentations
	Next Generation Tools Enabling a Revolution in Medicine (4.8 MB) Kevin Hrusovsky, Caliper Life Sciences
	The Future of Life Sciences: Fluidics & Imaging (2.5 MB) George Church, Harvard Medical School

Small Molecule Drug Discovery
	Caliper Profiling Service in GNF Drug Discovery (183 KB) Yong Jia, Genomics Institute of Novartis Research Foundation
	Pharmacological Inhibition of a Kinase involved in Insulin Signaling (247 KB) Siobhan Malaney, Formerly from Tanabe
	Cathepsin S Inhibitor Drug Development in a Virtual Company Model Using Caliper Discovery Alliances and Services (1.8 MB) Leslie Holsinger, Virobay
	Development, Validation and Implementation of an Assay for Identifying Inhibitors of Soluble Adenyl Cyclase Using the Caliper LC3000 (1.5 MB) Derek Hook, University of Minnesota
	Internal Kinase Selectivity Screening Made EZ (604 KB) Laurie Lebrun, Celgene Corporation
	The Use of Caliper LifeSciences Microfluidic Technology to Define a New Discovery Paradigm Adam Shutes, EMD Serono
	Metabolic Stability: 384 or 96, What's Your Throughput? Mark Snyder, Pfizer
	Promoting Illiteracy in Epigenetics: "Channeling" Chemical Probes for Methyl-Lysine Tim Wigle, University of North Carolina
	Supporting Kinase Discovery Progams Wtih the Caliper EZReader Bill Janzen, University of North Carolina
	Characterization of Slow Binding HDAC Inhibitors by Caliper Assay Yan-Ling Zhang, Broad Institute
	Application of Label-Free Assay Technology in Drug Discovery Services Scott Perschke, Caliper Discovery Alliances & Services
	The Value of Microfluidics as a Tool for Screening Jon Wingfield, Astra Zeneca

Biologics/Vaccines/Protein Science
	Analytical Capabilities of LabChip Technology (711 KB) Migani Damiano, Biogen Idec Pharmaceuticals
	LabChip GXII for High Throughput Analysis of Protein Quality Bahram Fathollahi, Caliper Life Sciences
	PhyNexus Separation and Purification with Caliper Robotics and LabChip Technologies Solutions for High Throughput Protein Analytics (2.8 MB) Christopher Suh, PhyNexus Inc.
	The Macrolab: Harnessing the Power of Automation to Solve Problems in Cloning and Protein Purification (2.4 MB) Abbey Hartland, MacroLab Core Facility, University of CA - Berkeley
	Fully Automated Sample Processing and HTP Microchip CGE Analysis for Rapid Identification of Microbial Production Strains Pfēnex Expression Technology (2.4 MB) Jeff Allen, Pfenex Inc.
	Implementation of LabChip Methods in Quality Control to Replace SDS-PAGE for Release and Stability Testing (702 KB) Stacey Traviglia, Biogen Idec
	High Throughput N-Linked Glycan Analysis in Support of Cell Line Screening (3.5 MB) Peter Bryngelson, Biogen Idec
	Novel Analytical Technology to Support Biologics Development: Caliper GX II Biologics Development: Caliper GX II System Application Evaluation (176 KB) Mei Lin, Bristol-Myers Squibb
	Replacing SDS-PAGE: comparison of Caliper LC GXII to other CE platforms (763 KB) Michael Smith, GSK

Genomics/Molecular Diagnostics
	New Applications in Genomics (3.7 MB) Isaac Meek, Caliper Life Sciences
	Genome, Epigenome, and Transcriptome Study by Deep-Sequencing using Next Generation Sequencing Technology (4.5 MB) Ryan Kim, National Center for Genomic Resources
	High Throughput PCR process for Finishing Genomes (1.7 MB) Beverly Parsons, Los Alamos National Labs - Joint Genome Institute
	High-Throughput Nucleic Acid Purification solutions on Zephyr Genomics Workstation (3.9 MB) Mimi Ly, Machery Nagel (Bjoern Henze)
	Microfluidic Protein Analysis at the Seattle Structural Genomics Center for Infectious Disease (2.9 MB) Amy Raymond, Emerald Biostructures
	Caliper LabChip GX Development and Implementation (1.0 MB) Dave Olsen, Access Genetics
	DNA Polyermase Development via Microfluidics and Database-Integrated Analysis (1.0 MB) Nicole Nichols, New England BioLabs Inc.
	Integration of the Caliper GX as a Quality Checkpoint for High Throughput Next Generation Sequencing Sample Preparation (1.4 MB) Andrew Barry, Broad Institute
	Nextera™ NGS Library Preparation: From Nanograms of DNA to Sequencer-Ready Libraries in Under Two Hours (2.0 MB) Nick Caruccio, Epicentre Biotechnologies
	Coupling the Transgenomic SURVEYOR® Scan K-RAS Mutation Detection Kit and COLD-PCR technology with the Caliper LabChip® GX System (1.1 MB) Ben Legendre, Transgenomic
	Annotation and Phenotypic Analysis of Cancer-Associated Alternative Splicing (3 MB) Roscoe Klick, University of Sherbrooke

Preclinical Imaging Applications & Technologies
	Optical Imaging of Cerenkov Light Generation From Positron-Emitting Radiotracers Matthew Silva, Millennium, The Takeda Oncology Company
	Applications for Optical Imaging using Positron-Emitting Radiotracers Robbie Robertson, Millennium, The Takeda Oncology Company
	IVIS and Humanized Mouse Models: Applications for Stem Cells, Viruses, Malaria Jennifer Moffat, SUNY Upstate Medical University

COG 2009 Presentations

	Chemical Genomic Approaches to Discovery Utilizing Caliper LabChip Technology William Janzen, University of North Carolina at Chapel Hill
	Automation in Drug Development: Challenges and Rewards Drané O’Brien, Boehringer Ingelheim Pharmaceuticals, Inc.
	Strategy, Struggles, and Success of Strategy, Struggles, and Success of Monitoring Process Related Impurities Monitoring Process Related Impurities with Automation Karen Blank, Biopharmaceutical Analysis, Wyeth
	Biopharmaceutical Production Using Pfēnex Expression Technology™ and HTP Microchip-SDS-CGE Jeff Allen, Pfēnex, Inc.
	Identification of Unknown Target Antigens using Target Antigens using PhyNexus Technology Claudia Fieger & Tim Hotaling, Macrogenics
	Development of an Automated Kinase Screening Platform Using the LabChip EZ Reader II Adam Shutes, EMD Serono Research Institute
	Caliper Automation: Hard at Work for Adnexus A Bristol Myers Squibb R&D Company Alex Bush, Adnexus
	High-Throughput Screening for Protein Engineering of Industrial Enzymes Jeffrey V. Miller, Genencor
	New Technologies for Enhanced Biopharmaceutical Analysis Nathan A. Lacher, Pfizer
	Assay Development and Inhibitor Characterization For Protein Kinases Using an LC 3000 Jeffery Hirsch, Pfizer
	Compounds That Target Host Cell Proteins Prevent Varicella-Zoster Virus Replication in Culture, Ex-Vivo, and in SCID-Hu Mice Jenny Rowe, SUNY Upstate Medical University
	Kinase Profiling Using a Mobility Shift Assay Platform and its Applications Masaki Gouda, Carna Biosciences
	Caliper Technology & Automated Kinase Screening at EMD Serono Adam Shutes, EMD Serono
	Caliper LabChip Technology in the Paralell Development of Small Molecule Inhibitors of Tyro3, Axl, and Mer (TAM) Kinases Amy Van Deusen, University of North Carolina at Chapel Hill
	Selectivity Profiling and Mechanistic Characterization of Phosphodiesterase Inhibitors using a Microfluidic Assay Edmond Massuda, Caliper Discovery Alliances & Services (CDAS)
	Genetic Screens in Human Tumor Cells Edward Richards, Harvard Medical School
	Analytical Capabilities of LabChip Technology Sharmila Babu, Biogen ICEC
	Coupled Assays for Analysing Enzymatic Activities of Proteins Involved in the cAMP Signaling Pathway Kornelia Hampel, Biaffin GmbH & CO KG
	Using LabChip 3000 for Phosphatase Screening Carola Seyffarth & Andreas Oder, Screening Unit AG Kries, FMP

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