Light Producing Cells (Bioware® & Bioware® Ultra) and Microorganisms
Caliper offers a wide range of bioluminescent cell lines, microorganisms and biofilms which are used in conjunction with our IVIS imaging systems.
Our light producing cell lines can be used to establish orthotopic mammary gland tumors, experimental lung metastasis by intravenous injection or spontaneous metastasis from a primary tumor site, or establish subcutaneous or metastatic tumor models. Cell line models are also available that link luciferase expression to signal transduction pathways that are key to the oncogenic process. These models offer the ability to track activation of factors that signal cell death or survival, or angiogenesis.
We also provide a wide range of bioluminescent pathogenic bacteria (both Gram-positive and Gram-negative) and a number of bioluminescent fungal strains that can be used for drug discovery both in vitro and in vivo (including biofilm models) when used with our imaging systems.
