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Products and Contract Services

IVIS® 3D Series

Overview


Sign up for our IVIS User Group Meeting on Tuesday, September 9th and Wednesday, September 10th in Nice, France (in conjunction with SMI)! 




The IVIS Imaging System 3D Series is the first and only commercial 3D bioluminescent imaging system. It uses Xenogen’s novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals. 

The IVIS Imaging System 3D Series offers rotational axis imaging of bioluminescent and fluorescent light sources within living animal models. With a unique optomechanical design (patent pending), the IVIS 3D provides eight imaging views about the longitudinal axis of the animal without physically rotating the animal or the CCD camera. A 3D diffuse tomography version of Living Image® software analyzes bioluminescent images to provide the in vivo source brightness, location, and size. The spatial resolution of the reconstruction is 1–3 mm, depending on source location.

For more information in our IVIS® 3D Series imaging system please click the button below and complete our product & services inquiry form. 

Request a Quote

or contact David Panzarella at +1-845-735-1921 or David.Panzarella@caliperls.com.




Applications

• Oncology Research (pdf)
• Infectious Disease (pdf)
• Inflammation (pdf)
• Metabolic Diseases (pdf)
• Neurology
• Gene Therapy (pdf)
• Stem cell Biology
• Cardiovascular Disease (pdf)
• Immunology & Transplantation Biology
• Toxicology (pdf)
• Drug Metabolism Studies (pdf)

Features

• High-sensitivity in vivo bioluminescence imaging
• Light-tight imaging chamber
• Heated stage to maintain optimum body temperature
• Motor controlled stage, filter wheel, lens position, and f-stop
• Unique optomechanical design (patent pending) for 3D image acquisition
• Structured light Illuminator for estimation of 3D surface topography of an animal.
• Living Image® software for 3D diffuse tomographic reconstruction and analysis of bioluminescent images to provide in vivo source brightness, location, and size.
• NIST traceable absolute calibrations

Demos

Our product can be demonstrated at our facility in Hopkinton, Massachussetts or other Caliper Life Sciences offices worldwide.  Please contact your local Caliper Representative to arrange a demo.

Specifications

Power Requirements
15 Amps at 120V

Dimensions
Imaging Chanber Interior Size: 39cm X 45cm x 48cm Imaging System Space Requirement: 46cm X 46cm X 51cm

Camera Sensor
Back-thinned, back-illuminated Grade 1 CCD

CCD
Size 2.7 x 2.7 cm
Operating Temperature -90°C

Imaging Pixels
2048 x 2048

Quantum Efficiency
>85% 500 – 700 nm; >30% 400 – 900nm

Pixel Size
13.5 microns

Minimum Detectable Radiance
100 photons/s/sr/cm2

Field of View (FOV)
Minimum FOV 15 x 15 cm
Maximum FOV 15 x 15 cm

Minimum Image Pixel Resolution
80 microns

f/stop Range
f/1 - f/16

Read Noise
< 3 electrons for bin=1,2,4; < 5 electrons for bin=8,16

Dark Current (Typical)
<120 electrons/s/cm2 or 2 x 10-4 electrons/s/pixel

Fluorescence Capability
Option

Filter Slots
Fluorescence Excitation 12 (with XFO option)
Fluorescence Emission 8

Fluorescence Filters
Excitation 8 (with XFO option)
Emission 4 (with XFO option)

Spectral Imaging Filters
3; 550 – 585, 585 – 620, 620 – 700 nm

Fluorescence Bkg. Subtraction Filters
Yes (with XFO option)

Heated Chamber
up to 32°C

Diffuse Tomography Software
Yes

Gas Anesthesia
Yes

Computer
2.8 GHz, 1 GB RAM, RW CD/DVD, 80 GB HD, 20” flat screen monitor