IVIS® Lumina XR

Introducing the IVIS Lumina XR with industry leading Fluorescence, Bioluminescence and now X-Ray. All-In-One!
IVIS Lumina XR
• Uncompromised
• Multimodal
• Simplified
• Flexible
Multimodal Imaging
IVIS Lumina XR offers all the benefits of IVIS Lumina together with x-ray. Precise optical and X-ray overlay allows you to bring your optical signal into anatomical context.
Caliper Life Science’s Living Image software automates all the controls and settings required for seamless image acquisition and processing. Typical X-ray image acquisitions take only 10 seconds and can be overlaid with both optical and photographic images.
Superior Optical Imaging with Spectral Unmixing
The IVIS Lumina XR is capable of imaging all common fluorescent and bioluminescent reporters or dyes. The system is equipped with up to 21 filter sets to image reporters that emit from green to near-infrared.
High resolution, sharp cut-off filters are simply interchangeable to achieve the highest performance, sensitivity and spectral unmixing. IVIS Lumina XR also accommodates Petri dishes or micro-titer plates for in vitro imaging. The system can incorporate premium animal handling features such as a heated stage, gas anesthesia connections and a syringe injection system for simultaneous compound administration.
Living Image Software
The Living Image software yields high-quality, reproducible, quantitative results incorporating instrument calibration, background subtraction and the image algorithms. Simple user guided spectral unmixing allows detection and separation of multiple reporters, and Living Image provides the precise overlay to see your optical reporters together with anatomical surface or X-ray features.
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or contact David Panzarella at +1-845-735-1921 or David.Panzarella@caliperls.com
Applications
• Infectious Disease
• Inflammation
• Metabolic Disease
• Neurology
• Gene Therapy
• Stem Cell Biology
• Cardiovascular Disease
• Immunology & Transplant Biology
• Toxicology (PDF)
• Drug Metabolism Studies
Features
Inside the IVIS Lumina XR
• High-sensitivity in vivo and in vitro imaging of fluorescence and bioluminescence
• Back-thinned, back-illuminated grade 1 CCD provides high quantum efficiency over the entire visible to near-infrared spectrum
• Light-tight imaging chamber
• 8 position emission filter wheels
• 10 position excitation filter wheels
• 5 filter wheel choices for a broad range of fluorescence applications
• LED lamps for photographic images
• Heated stage to maintain optimum body temperature
• Automated motor controlled stage, filter wheel, lens position, and f-stop
X-Ray Module
• Average X-ray acquisition in less than 10 seconds
• Radiation shielded Cabinet
• Exceeds standards set by the US FDA Center for Devices and Radiological Health (21 CFR-1020.40)
• Automated image integration to overlay with Bioluminescence , Fluorescence and Photograph
Optional Accessories
• Optical Zoom Lens attachment for close up and high resolution X-ray images (available winter 2010)
• Gas anesthesia ports and 3 position manifold within imaging chamber allow anesthesia to be maintained during imaging sessions
• Syringe injection system allows the user to acquire real time functional responses to compounds, by defining amount, flow rate and start time of the pump through Living Image.
Specifications
Power Requirements |
|
| 6A at 120V | |
Dimensions |
|
| System space requirements: 48 x 71 x 104 cm (W x D xH) | |
Operating System Software |
|
| Living Image Software. 1 acquisition copy and 1 analysis copy | |
Camera Sensor |
|
| Back-thinned, back-illuminated, Cooled Grade 1 CCD, frame transfer | |
CCD |
|
| Size | 13mm x 13mm |
| Operating Temperature | -90°C |
Imaging Pixels |
|
| 1024 x 1024 | |
Quantum Efficiency |
|
| >85% 500 – 700 nm; >30% 400 – 900nm | |
Pixel Size |
|
| 13.0 microns | |
Minimum Detectable Radiance |
|
| 100 photons/s/sr/cm2 | |
Field of View (FOV) |
|
| Minimum FOV | 5 x 5 cm |
| Maximum FOV | 12.5 x 12.5 cm |
Minimum Image Pixel Resolution |
|
| 50 microns | |
Dark Current (Typical) |
|
| <3 x10-4e-/pixels/s | |
Fluorescence Filters |
|
| Excitation | 10 high resolution filters standard on all instruments |
| Emission | 5 sets available to choose from: One standard resolution set of 4 filters and 4 sets of 7 high resolution filters |
Computer |
|
| Minimum specifications: 2.8 GHz, 1 GB RAM, RW CD/DVD, 80 GB HD, 20" flat screen monitor | |
Lens |
|
| f/.95 – f/16, 50 mm | |
Stage Temperature |
|
| 20 – 40°C | |
Imaging Chamber Dimensions |
|
| 48 x 38 x 43 cm (W x D x H) | |
Radiation shielded Cabinet |
|
| Exceeds standards set by the US FDA Center for Devices and Radiological Health (21 CFR-1020.40) | |
Radiation |
|
| < 0.1 mR/hr | |
Automated aluminum filter |
|
| 0.4 mm | |
Plate Voltage Range |
|
| 4-40kVp | |
Tube Current Range |
|
| 1-100uA | |
Anode Material |
|
| Tungsten | |
Typical X-Ray Image Acquisition Time |
|
| 10s | |
Window Filtration |
|
| 0.127mm beryllium | |
Scintillator |
|
| Automated CsI plate placement during X-Ray acquisition | |
Imaging System Space Requirement |
|
| 48 x 71 x 104 cm (W x D x H) | |
Imaging Chamber Interior Dimension |
|
| 43 x 38 x 43 cm (W x D x H) | |
Computer (Minimum specifications) |
|
| 2.8 GHz, 1 GB RAM, RW CD/DVD, 80 GB HD, 20” flat screen monitor | |
Living Image Software |
|
| 1 acquisition copy and 1 analysis copy of Living Image software | |

