IVIS® 200 Series
Overview
Sign up for our IVIS User Group Meeting on Tuesday, September 9th and Wednesday, September 10th in Nice, France (in conjunction with SMI)!
The IVIS Imaging System 200 Series is an advanced single-view 3D optical imaging system designed to improve quantitative outcomes of in vivo imaging. It uses Xenogen’s novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
A single-view 3D imaging system designed for high throughput, the IVIS® 200 Series' instrumentation and software allow researchers to better account for the effects of photon absorption and scattering in tissue, making bioluminescent source measurements more quantitative. Key features on the IVIS Imaging System 200 Series include a custom lens with 5-position carousel and adjustable field of view of 4-26 cm, more uniform light collection, and improved resolution with single cell sensitivity for in vitro use. An integrated fluorescence system (400-900 nm) allows easy switching between fluorescent and bioluminescent spectral imaging applications, while a laser scanner provides 3D surface topography for single-view diffuse tomographic reconstructions of internal sources.
For more information in our IVIS® 200 Series imaging system please click the button below and complete our product & services inquiry form.
or contact David Panzarella at +1-845-735-1921 or David.Panzarella@caliperls.com.
Applications
• Oncology Research (pdf)
• Infectious Disease (pdf)
• Inflammation (pdf)
• Metabolic Diseases (pdf)
• Neurology
• Gene Therapy (pdf)
• Stem cell Biology
• Cardiovascular Disease (pdf)
• Immunology & Transplantation Biology
• Toxicology (pdf)
• Drug Metabolism Studies (pdf)
Features
• High throughput (5 mice) with 26 cm field of view
• High resolution (to 60 microns) with 3.9 cm field of view
• Dual 12-position emission filter wheels (24-position total) and 12-position excitation wheel
- A set of four filter pairs for fluorescent imaging come standard with the instrument, in addition to a set of four background filters for subtraction of tissue autofluorescence
• 25 x 25 cm alignment grid on the imaging platform ensures consistent accurate placement of animals for imaging
• Spectral imaging filters that acquire images at different wavelengths (ranging from 560 nm to 660 nm) facilitate 3D diffuse tomographic reconstruction and determination of the depth and location of a bioluminescent reporter
• Heated animal shelf (up to 40˚ C)
• NIST traceable absolute calibrations
• Gas anesthesia inlet and outlet ports
Demos
Specifications
Power Requirements |
|
| 20 Amps for 120VAC or 10 Amps for 230VAC | |
Net Weight |
|
| <275 kg/600 lbs | |
Camera Sensor |
|
| Back-thinned, back-illuminated Grade 1 CCD | |
CCD |
|
| Size | 26 x 26 mm |
| Operating Temperature | Nominal –105 • C |
Imaging Pixels |
|
| 2048 x 2048 | |
Quantum Efficiency |
|
| >85% 500–700 nm; >50% 350-950 nm | |
Pixel Size |
|
| >13.5 µm square | |
Minimum Detectable Radiance |
|
| <70 photons/s/sr/cm2 | |
Minimum Image Pixel Resolution |
|
| 60 µm (at f/1) | |
Read Noise |
|
| <5 electrons RMS | |
Dark Current (Typical) |
|
| <100 electrons/s/cm2 | |
Filter Slots |
|
| Fluorescence Excitation | 25 mm diameter 12-position (11-filter capacity) |
| Fluorescence Emission | 60 mm diameter 24-position (22-filter capacity) |
Lens |
|
| f/1– f/8, 1.5x, 2.5x, 5x, 7.5x, 10x magnifications | |
Field of View |
|
| 3.9 x 3.9 cm to 26 x 26 cm (3.9, 6.5, 13, 19.5, 26 cm) | |
Scanning Laser |
|
| <1 mW power at 532 nm | |
Stage Temperature |
|
| Ambient to 40 ˚ C | |
Imaging Chamber Dimensions |
|
| 51 cm x 51 cm x 66 cm (D x W x H) | |
Lamp |
|
| 150 W Quartz halogen 3250 • Kelvin | |
Fluorescence Field of View |
|
| 6.5, 13, 19.5, 26 cm (fluorescence not available at 3.9 cm field of view) | |
Background (autofluorescence and leakage) |
|
| <3 part in 106 typical | |
