Skip to content

Products and Contract Services

IVIS® 100 Series

Overview


Sign up for our IVIS User Group Meeting on Tuesday, September 9th and Wednesday, September 10th in Nice, France (in conjunction with SMI)! 

The IVIS Imaging System 100 Series from Caliper Life Sciences is a highly sensitive and large field of view imaging system that offers users the flexibility to image fluorescent and/or bioluminescent reporters both in vivo and in vitro. It relies on Xenogen’s novel patented optical imaging technologies to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.

The IVIS 100 offers an adjustable field of view of 10-25 cm, allowing 5 mice or 2 large rats to be imaged. The system features a 25 mm (1.0 inch) square back-thinned, back-illuminated CCD, which is cryogenically cooled to –90°C via a closed cycle refrigeration system (without liquid nitrogen) to minimize electronic background and maximize sensitivity. A patented and extremely light-tight, low background imaging chamber allows the IVIS 100 Series to be used in standard lab lighting environments. The system includes animal handling features such as a heated sample shelf, gas anesthesia connections, and an optional full gas anesthesia system. The IVIS Imaging System 100 Series is highly automated with all hardware motor movement, imaging parameters, and image analysis controlled via Living Image® software.

For more information in our IVIS® 100 Series imaging system please click the button below and complete our product & services inquiry form. 

Request a Quote

or contact David Panzarella at +1-845-735-1921 or David.Panzarella@caliperls.com.




Applications

• Oncology Research (pdf)
• Infectious Disease (pdf)
• Inflammation (pdf)
• Metabolic Diseases (pdf)
• Neurology
• Gene Therapy (pdf)
• Stem cell Biology
• Cardiovascular Disease (pdf)
• Immunology & Transplantation Biology
• Toxicology (pdf)
• Drug Metabolism Studies (pdf)

Features

• High-sensitivity in vivo and in vitro imaging of bioluminescence and fluorescence
• Adjustable field of view from 10-25 cm (for up to 5 mice or 2 large rats)
• Camera CCD provides high quantum efficiency over the entire visible to near-infrared spectrum and is thermo-electrically (Peltier) cooled to -90 C to ensure low dark current and low noise.
• Light-tight imaging chamber
• 6 position optical filter wheel
• Heated stage to maintain optimum body temperature
• Motor controlled stage, filter wheel, lens position, and f-stop
• NIST traceable absolute calibrations
• Gas anesthesia inlet and outlet ports

Demos

Our product can be demonstrated at our facility in Hopkinton, Massachussetts or other Caliper Life Sciences offices worldwide.  Please contact your local Caliper Representative to arrange a demo.

Specifications

Power Requirements
15 Amps at 120V

Dimensions
Imaging Chamber Interior Size : 48cm x 71cm x 104cm Imaging System Space Requirement: 43cm x 38cm x 43cm

Camera Sensor
Back-thinned, back-illuminated Grade 1 CCD

CCD
Size 2.7 x 2.7 cm
Operating Temperature -90°C

Imaging Pixels
2048 x 2048

Quantum Efficiency
>85% 500 – 700 nm; >30% 400 – 900nm

Pixel Size
13.5 microns

Minimum Detectable Radiance
100 photons/s/sr/cm2

Field of View (FOV)
Minimum FOV 10 x 10 cm
Maximum FOV 25 x 25 cm

Minimum Image Pixel Resolution
50 microns

Read Noise
< 3 electrons for bin=1,2,4; < 5 electrons for bin=8,16

Dark Current (Typical)
<120 electrons/s/cm2 or 2 x 10-4 electrons/s/pixel

Fluorescence Capability
Option

Filter Slots
Fluorescence Excitation 12 (with XFO option)
Fluorescence Emission 6

Fluorescence Filters
Excitation 8 (with XFO option)
Emission 4 (with XFO option)

Fluorescence Bkg. Subtraction Filters
Yes (with XFO option)

Computer
2.8 GHz, 1 GB RAM, RW CD/DVD, 80 GB HD, 20” flat screen monitor

Lens
f/.95 – f/16, 50 mm

Stage Temperature
20 – 40°C