CYP3A4 (h), CYP3A4 (h)
| Cat#: | 400-0098 |
| Species: | Human |
| Region | Recombinant expressed in insect cells |
| Substrate | Dibenzyl fluorescein (DBF) |
| Substrate [M] | 0.5E-6 |
| Km (enzyme affinity) | 2.1E-6 M |
| Vmax | 14 pmol fluorescein/pmol CYP3A4/min. |
| Reaction | DBF + NADPH -> Fluorescein + NADP+ |
| Method | Fluorescence |
| Reference Compound | Ketoconazole
IC50 = 0.048 μM |
